Study finds amplification of multiple cell-growth genes in some brain tumors
Thursday, December 1, 2011 - 13:02
in Biology & Nature
A small percentage of the deadly brain tumors called glioblastomas, which usually resist treatment with drugs targeting mutations in cell-growth genes, appears to contain extra copies of two or three of these genes at the same time. The surprising discovery by a Massachusetts General Hospital (MGH)-based research team has major implications for the understanding of tumor biology including the evolution of tumor cell populations and for targeted cancer therapies.