Amplification of multiple cell-growth genes found in some brain tumors
Thursday, December 1, 2011 - 22:30
in Biology & Nature
A small percentage of the deadly brain tumors called glioblastomas, which usually resist treatment with drugs targeting mutations in cell-growth genes, appears to contain extra copies of two or three of these genes at the same time. The surprising discovery has major implications for the understanding of tumor biology – including the evolution of tumor cell populations – and for targeted cancer therapies.