Loss of protein SPDEF allows prostate cancer cells to gain foothold at possible sites of metastasis

Friday, July 6, 2012 - 08:31 in Health & Medicine

Prostate cancer doesn't kill in the prostate — it's the disease's metastasis to other tissues that can be fatal. A University of Colorado Cancer Center study published this week in the Journal of Biological Chemistry shows that prostate cancer cells containing the protein SPDEF continue to grow at the same pace as their SPDEF- cousins, but that these SPDEF+ cells are unable to survive at possible sites of metastasis.

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