Open science journal publishes attempt to reproduce high-profile stem cell acid bath study
Thursday, May 8, 2014 - 12:31
in Biology & Nature
In a study published today in F1000Research, Professor Kenneth Lee of the Chinese University of Hong Kong reveals the full experimental results of an attempt to replicate a controversial study published in Nature recently that suggested that bathing somatic cells in acid can reprogram them to induced pluripotent stem cells (iPS cells). With systematically collected and fully available data, Lee and his colleagues report that carefully replicating the original acid-treatment method does not induce pluripotency in two types of mouse somatic cells, including those used in the original study.