First atlas of body clock gene expression informs timing of drug delivery

A new effort mapping 24-hr patterns of expression for thousands of genes in 12 different mouse organs – five years in the making – provides important clues about how the role of timing may influence the way drugs work in the body. A study detailing this veritable "atlas" of gene oscillations, never before described in mammals, is published this week in the Proceedings of the National Academy of Sciences. The research was led by John Hogenesch, PhD, professor of Systems Pharmacology and Translational Therapeutics, in the University of Pennsylvania's Perelman School of Medicine.

Read the whole article on Physorg

More from Physorg