First atlas of body clock gene expression informs timing of drug delivery
Tuesday, October 28, 2014 - 04:01
in Biology & Nature
A new effort mapping 24-hr patterns of expression for thousands of genes in 12 different mouse organs – five years in the making – provides important clues about how the role of timing may influence the way drugs work in the body. This study, detailing this veritable “atlas” of gene oscillations, has never before been described in mammals. Nearly half of all genes in the mouse genome oscillate on a 24-hour schedule somewhere in the mouse body.