SUMO protein guides chromatin remodeler to suppress genes
Monday, April 27, 2009 - 10:42
in Biology & Nature
BOSTON (April 27, 2009) --In an in vitro study, led by Grace Gill, PhD, Tufts University School of Medicine, researchers discovered how a protein called SUMO (Small Ubiquitin-related Modifier) guides an enzyme complex that alters the structure of chromatin to regulate expression of genes. Chromatin is a compacted mass of DNA and protein that make up chromosomes.