Landmark study sheds new light on human chromosomal birth defects

Wednesday, September 16, 2009 - 15:08 in Biology & Nature

TALLAHASSEE, Fla. -- Using yeast genetics and a novel scheme to selectively remove a single protein from the cell division process called meiosis, a cell biologist at The Florida State University found that when a key molecular player known as Pds5 goes missing, chromosomes fail to segregate and pair up properly, and birth defects such as Down syndrome can result.

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