Diminuendo - new mouse model for understanding cause of progressive hearing loss

Scientists of Helmholtz Zentrum Muenchen, led by Professor Martin Hrabe de Angelis, director of the Institute of Experimental Genetics, have developed a new mouse model with a genetic mutant in which a single base of a specific microRNA seed region has been altered. Mice carrying this miR-96 mutation suffer progressive hearing loss as they get older. Moreover, if they carry two of these mutants, their sensory hair cells are impaired from birth on...

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