IKK may act as both inhibitor and promoter of Huntington's disease

The kinase IKK phosphorylates the protein mutated in Huntington's disease to promote its removal and neurone survival, but IKK may be a double-edged sword that increases neurotoxicity in later stages of the disease. The study, led by researchers from the University of California, Irvine, was published online 21 December in the Journal of Cell Biology (www.jcb.org)...

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