Systems biology helps to understand haematopoiesis

Our body reacts to blood loss by stimulating the production of red blood cells (erythrocytes). The cells of the haematopoietic (blood-forming) system in the bone marrow do so upon receipt of a signal by a hormone called erythropoietin, or Epo for short. This hormone is produced mainly by the kidney that increases the Epo level by up to a thousand-fold as a response to falling oxygen saturation of the blood...

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