Shifting forms: Penn study shows how variations of same protein affect immune response

Saturday, October 16, 2010 - 06:20 in Health & Medicine

How a T cell decides to make protein X, Y, or Z can have profound effects for fighting foreign invaders or staving off dire autoimmune reactions. Researchers at the University of Pennsylvania School of Medicine have identified the steps that control how different forms of an immune cell protein called CD45, which is critical for activating the immune system when faced with pathogens, are controlled in the arc of a body's immune response...

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