Mathematical model of the life cycle of red blood cells may predict risk of anaemia

A collaboration between a physician-researcher at Massachusetts General Hospital (MGH) and a mathematician from Harvard University has led to development of a mathematical model reflecting how red blood cells change in size and haemoglobin content during their four-month lifespan. In their report published online in PNAS Early Edition, John Higgins, MD, MGH Centre for Systems Biology and Department of Pathology, and L. Mahadevan, PhD, Harvard School of Engineering and Applied Sciences (SEAS), also describe how their model may be used to provide valuable clinical information...

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