Long-term use of osteoporosis medication associated with increased risk of atypical fractures

Older women who used bisphosphonates (medications that prevent loss of bone mass) for five years or more were more likely to experience 'atypical' fractures involving the femoral shaft (bone in the leg that extends from the hip to the knee) or subtrochanteric (fractures in the bone just below the hip joint), compared to women with less usage. However, the absolute risk of these 'atypical' fractures was low and bisphosphonate use was associated with a reduced risk of typical osteoporotic fractures, according to a study in the February 23 issue of JAMA...

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