How Proteins Talk To Each Other
Tuesday, September 22, 2009 - 21:14
in Biology & Nature
Investigators have identified novel cleavage sites for the enzyme caspase-3 (an enzyme that proteolytically cleaves target proteins). Using an advanced proteomic technique called N-terminomics, scientists determined the cleavage sites on target proteins and found, contrary to previous understanding, that caspase-3 targets a-helices as well as unstructured loops.