Mouse with human liver: New model for treatment of liver disease

How do you study -- and try to cure in the laboratory -- an infection that only humans can get? A team of researchers does it by generating a mouse with an almost completely human liver. This "humanized" mouse is susceptible to human liver infections and responds to human drug treatments, providing a new way to test novel therapies for debilitating human liver diseases and other diseases with liver involvement such as malaria.

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