Depression associated with sustained brain signals: Genetic mutation in mice elevates their risk of stress-induced depression

Genetics may have some role in the predisposition of some people to the effects of stress, as changes in a gene that regulates brain signals are associated with depression. Scientists have now created a mouse with these same genetic changes. These mice show signs characteristic of depression and social anxiety and they provide some insight into the neurological effects that may influence vulnerability to depression in humans.

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