Lollipops and ice fishing: Molecular rulers used to probe nanopores

Using a pair of exotic techniques including a molecular-scale version of ice fishing, researchers have developed methods to measure accurately the length of "nanopores," the miniscule channels found in cell membranes. The team's "molecular rulers" could serve as a way to calibrate tailor-made nanopores -- whose diameters are nearly 10,000 times smaller than that of a human hair -- for applications such as rapid DNA analysis.

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