Molecular discovery suggests new strategy to fight cancer drug resistance

Scientists have found a way to disable a common protein that often thwarts chemotherapy treatment of several major forms of cancer. The researchers discovered, surprisingly, that they could exploit a small portion of this anti-death protein, called MCL-1, to make a molecular tool that specifically blocked MCL-1's "pro-survival" action, allowing standard cancer drugs to kill the tumor cells by apoptosis, or programmed cell death.

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