Cellular housekeeper, and potential target of obesity drugs, caught in action

Monday, August 2, 2010 - 13:14 in Biology & Nature

New clues emerge about how a molecular machine breaks down unwanted proteins in cells, a critical housekeeping chore that helps prevent diseases such as cancer. The insights, thanks to the first molecular-scale description of a giant enzyme called tripeptidyl peptidase II, could also inform the development of obesity-fighting drugs.

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