Gene therapy prevents memory problems in mice with Alzheimer's disease

Sunday, November 28, 2010 - 22:30 in Health & Medicine

Scientists have discovered a new strategy to prevent memory deficits in a mouse model of Alzheimer's disease (AD). Humans with AD and mice genetically engineered to simulate the disease have abnormally low levels of an enzyme called EphB2 in memory centers of the brain. Improving EphB2 levels in such mice by gene therapy completely fixed their memory problems.

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