Impaired clearance, not overproduction of toxic proteins, may underlie Alzheimer’s disease

In Alzheimer's disease, a protein fragment called beta-amyloid accumulates at abnormally high levels in the brain. Now researchers have found that in the most common, late-onset form of Alzheimer's disease, beta-amyloid is produced in the brain at a normal rate but is not cleared, or removed from the brain, efficiently.

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