Promising clue to mechanism behind gene mutation that causes Parkinson's disease
Friday, March 25, 2011 - 15:32
in Biology & Nature
Researchers have discovered a way that mutations in a gene called LRRK2 may cause the most common inherited form of Parkinson's disease. The study, published online this month in the journal Public Library of Science, shows that upon specific modification called phosphorylation, LRRK2 protein binds to a family of proteins called 14-3-3, which has a regulatory function inside cells.