Jekyll into Hyde: Breathing auto emissions turns HDL cholesterol from 'good' to 'bad'

Academic researchers have found that breathing motor vehicle emissions triggers a change in high-density lipoprotein (HDL) cholesterol, altering its cardiovascular protective qualities so that it actually contributes to clogged arteries. The finding, shown in mice, reveals how car emissions activate the early cell and tissue damage called oxidation that causes inflammation leading to hardening of the arteries and HDL cholesterol may play a key role.

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