Communication Breakdown in Brain Caused by a Gene Defect May Contribute to Schizophrenia

More than 15 years after a genetic variant was shown to predispose its carriers to schizophrenia, scientists have finally uncovered how the chromosomal abnormality might cause symptoms of the brain disorder . By studying mice with a similar gene defect, the research team from Columbia University Medical Center linked abnormalities in behavior to a faulty connection between the hippocampus and the prefrontal cortex--two brain areas important for learning and memory. [More]

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