Improved understanding of protein complex offers insight into DNA replication initiation mechanism basics
Wednesday, April 8, 2015 - 16:30
in Biology & Nature
A clearer understanding of the origin recognition complex (ORC) - a protein complex that directs DNA replication - through its crystal structure offers new insight into fundamental mechanisms of DNA replication initiation. This will also provide insight into how ORC may be compromised in a subset of patients with Meier-Gorlin syndrome, a form of dwarfism in humans.