Is biopsy avoidable on diagnosis of celiac disease?

A research team from Argentina explored the accuracy of all available serological markers in diagnosing the disorder in the theoretical context of avoiding the invasive intestinal biopsy. They found that the DGP/tTG Screen assay was the best initial test for suspected celiac disease. Combinations of assays might be able to diagnose celiac disease accurately, avoiding biopsy in almost 92 percent of subjects under study.

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