Electrical activity in developing brain influences choice of neurotransmitter

Wednesday, July 28, 2010 - 11:07 in Biology & Nature

Cascades of genetic signals determine which neurotransmitter a brain cell will ultimately use to communicate with other cells. Now a pair of reports from biologists at the University of California, San Diego, have shown for the first time that electrical activity in these developing neurons can alter their chemical fate -and change an animal's behavior -by tweaking this genetic program.

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