Seasonal changes may influence the efficacy of vaccination against diabetes
Wednesday, February 1, 2012 - 17:00
in Health & Medicine
The development of a medicine for patients with type 1 diabetes mellitus, based on autoantigen GAD65, received a setback following crucial clinical phase 3 trials that failed to show significant effects. One possible explanation may be seasonal variations in the immune system, claim those responsible for the study that was published in the New England Journal of Medicine (NEJM).