A pathway to bypass DNA lesions in the replication process is experimentally shown
Monday, December 3, 2012 - 08:30
in Biology & Nature
DNA lesions are really common —about one million individual molecular lesions per cell per day— because its long strands usually have one missing base or are damaged. These lesions can stall the DNA replication process, what can lead to the cell death. To avoid it, there are several pathways to bypass lesions in order to continue with the process of DNA replication. One of these processes has been entirely reproduced in vitro using some techniques of manipulation of single-molecules in a study published today in Science, led by the researcher of the University of Barcelona Maria Mañosas.