New tool developed for profiling critical regulatory structures of RNA molecules

A molecular technique that will help the scientific community to analyze—on a scale previously impossible—molecules that play a critical role in regulating gene expression has been developed by a research team led by a chemist and a plant biologist at Penn State University. The scientists developed a method that enables more-accurate prediction of how ribonucleic acid molecules (RNAs) fold within living cells, thus shedding new light on how plants—as well as other living organisms—respond to environmental conditions. A paper by the research team—led by Sarah M. Assmann, Waller Professor of Biology, and Philip Bevilacqua, professor of chemistry—is scheduled for early online publication in the journal Nature on 24 November 2013.

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