Genetic molecular mechanisms of neural development identified
Friday, March 7, 2014 - 09:00
in Biology & Nature
Neural development is an extremely complex and highly orchestrated process, involving genetic cascades during which dozens of genes are activated at specific times and places. Polycomb-group (PcG) proteins play an important role by reversibly repressing the activity of a set of developmental regulatory genes. Now, Haruhiko Koseki, Takashi Kondo and colleagues from the RIKEN Center for Integrative Medical Sciences and RIKEN Brain Science Institute have revealed the mechanisms by which one member of the PcG protein family regulates the activity of a control gene called Meis2.