Immunologists present improved mass spectrometric method for proteomic analyses
When it comes to analyzing cell components or body fluids or developing new medications, there is no way around mass spectrometry. Mass spectrometry is a highly sensitive method of measurement that has been used for many years for the analysis of chemical and biological materials. Scientists at the Institute of Immunology of the University Medical Center of Johannes Gutenberg University Mainz (JGU) have now significantly improved this analytical method that is widely employed within their field. They have also developed a software program for the integrated analysis of measurement data called ISOQuant. Their optimized mass spectrometric workflow allows to identify and quantify significantly more proteins than before. The development of this enhanced method of measurement and the specially designed software is described in an article recently published in the prestigious journal Nature Methods.