Structure of sodium channels different than previously believed

Sodium channels are implicated in many serious conditions such as heart disease, epilepsy and pain, making them an important potential target for drug therapies. Unfortunately, there is still much scientists do not know about the molecules. New Cambridge research provides fresh and unexpected insight into the structure of sodium channels and, specifically, one of its components - β-subunit molecules - which are responsible for 'fine-tuning' the activity of the channel. The research is published in the most recent edition of the Journal of Biological Chemistry.

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