Mechanism safeguarding unique epigenome of oocytes and maternal fertility
Thursday, November 29, 2018 - 07:31
in Biology & Nature
In mammals, females have a limited supply of oocytes. Oocytes have a unique epigenome with approximately half the DNA methylation of sperm, and the most terminally differentiated somatic cells. Until recently, regulators of this unique DNA methylation pattern and its functional significance were unknown.