Designing synthetic receptors for precise cell control

Monday, May 22, 2023 - 08:23 in Physics & Chemistry

Biosensors are artificial molecular complexes designed to detect the presence of target chemicals or even biomolecules. Consequently, biosensors have become important in diagnostics and synthetic cell biology. However, typical methods for engineering biosensors focus on optimizing the interactions between static binding surfaces, and current biosensor designs can only recognize structurally well-defined molecules, which can be too rigid for "real-life" biology.

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