Diagnostic Eyedrops Could Make Patients' Eyes Light Up With Signs of Neurological Disease
Diagnosing the Brain by Gazing into the Eyes SheLovesGhosts via Wikimedia Neurodegenerative diseases like Parkinson's, Alzheimer's, or Creutzfeld-Jacobs are tough to diagnose. Outward symptoms can obviously be an indicator, but symptoms for many neuro-disorders overlap while protein biomarkers for each illness, called amyloids, are difficult to distinguish between. But researchers at UCSD are developing a new diagnostic tool that could soon let doctors diagnose a patient's neuro-degenerative condition simply by gazing into his or her eyes. Amyloids are fibrous protein aggregates with distinct structures--basically proteins that didn't fold quite the right way. This makes them distinctive as a group but difficult to distinguish between. Many neurological disorders like those mentioned above are associated with specific amyloids. Identify the amyloid, and you can identify the disorder. That's been difficult until now, but the UCSD team has developed a set of fluorescent markers that change colors depending on what amyloid they encounter. Amyloids accumulate...