Dynamic Molecular Mechanism To Keep Brain Activity Stable

Monday, July 13, 2009 - 10:28 in Biology & Nature

In the brain, many types of synaptic proteins are spatio-temporally regulated to maintain synaptic activity at a constant level. Here, scientists found that two types of palmitoylating enzymes finely-tune the location and function of a major synaptic protein, PSD-95, in different ways. They also found that this mechanism contributes to keeping synaptic activity stable when synaptic activity dynamically changes.

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