Stem cell derived neurons for research relevant to Alzheimer's and Niemann-Pick type C diseases

Stem cell derived neurons may allow scientists to determine whether breakdowns in the transport of proteins, lipids and other materials within cells trigger the neuronal death and neurodegeneration that characterize Alzheimer's disease and the rarer but always fatal neurological disorder, Niemann-Pick Type C, according to a recent presentation. Early defects in the intracellular physical transport system may be the driving force behind severe neuronal dysfunction.

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