Three brain diseases linked by toxic form of same neural protein

Researchers have found that three different degenerative brain disorders are linked by a toxic form of the same protein. Elk-1 was found in clumps of misshaped proteins that are the hallmarks of Parkinson's disease, Alzheimer's disease, and Huntington's disease. This suggests a molecular link between the presence of inclusions and neuronal loss that is shared across a spectrum of neurodegenerative disease. Identifying these links could open up novel avenues for therapeutic intervention.

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