Scientists find signals that make cell nucleus blow up like a balloon

The size of a cell's nucleus varies from one species to another, in different cell types and at different stages of development, and even with disease: many cancer cells develop larger nuclei as they become more malignant. Working with the African clawed frog, researchers have discovered two proteins that control the size of the nucleus. One imports lamin to shore up the nuclear envelope; the other controls importation.

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