Gene mutation signals a high risk of recurrence in some older acute-leukemia patients

Monday, December 12, 2011 - 16:30 in Health & Medicine

Older people with acute myeloid leukemia and normal looking chromosomes in their cancer cells have a higher risk of recurrence if they have mutations in the ASXL1gene, according to a new study. The study is the first to investigate the influence of these gene mutations on prognosis in these patients and in conjunction with other prognostic gene mutations. The findings could lead to more effective targeted therapies and improved cure rates for these patients.

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