New genetic subtype of lung cancer defined

Tuesday, January 31, 2012 - 14:30 in Health & Medicine

Investigators have defined the role of a recently identified gene abnormality – rearrangements in the ROS1 gene – in a deadly form of lung cancer. ROS1-rearranged tumors represent one to two percent of non-small-cell lung cancers, the leading cause of cancer death in the US. The researchers also show that ROS1-driven tumors can be treated with crizotinib and describe the remarkable response of one patient to crizotinib treatment.

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