Living human gut-on-a-chip: Tiny device simulates structure, microenvironment, and mechanical behavior of human intestine

Researchers have created a gut-on-a-chip microdevice lined by living human cells that mimics the structure, physiology, and mechanics of the human intestine -- even supporting the growth of living microbes within its luminal space. As a more accurate alternative to conventional cell culture and animal models, the microdevice could help researchers gain new insights into intestinal disorders and evaluate the safety and efficacy of potential treatments.

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