Scientists use light to uncover the cause of sickle cell disease
Tuesday, November 5, 2013 - 13:00
in Biology & Nature
In sickle cell disease, hemoglobin -- the oxygen-carrying component of blood -- forms fibers that stiffen red blood cells and cause life-threatening symptoms. Using light-scattering techniques to study the detailed thermodynamics of this process, researchers have determined the strength of the forces that hold these fibers intact. The information could be used to design therapies that interfere with the sickling process.