Single-cell genome sequencing gets better

Monday, November 11, 2013 - 13:00 in Biology & Nature

Researchers have generated the most complete genome sequences from single E. coli cells and individual neurons from the human brain. Preliminary data suggest that individual neurons from the same brain have different genetic compositions. The breakthrough comes from a new single-cell genome sequencing technique that confines genome amplification to fluid-filled wells with a volume of just 12 nanoliters.

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