'Intrabody' can mop up mutant protein in Huntington's disease model
Monday, May 26, 2008 - 02:49
in Biology & Nature
Scientists have created a tool for mopping up the clumps of mutant protein that drive neurodegeneration in Huntington's disease. Emory University researchers engineered a virus to make an intracellular antibody or "intrabody" against huntingtin, the protein whose mutant forms poison the brain cells of people with Huntington's.